Tasigna Side Effects Liver

If you already have liver damage or you re affected by liver damage while taking tasigna you have an increased risk of serious.
Tasigna side effects liver. Qtc prolongation and sudden death. Prolonged qt interval on ekg. Tell your doctor if you have serious side effects of tasigna including. Low levels of white blood cells.
Some side effects are more severe including swelling in the hands and feet rapid weight gain painful urination severe stomach pain high blood sugar and liver disease. Cold symptoms stuffy nose sneezing cough or sore throat. If experienced these tend to have a. During treatment with tasigna your doctor will do tests to check for side effects.
Low amount of sodium in the blood. From 2007 to september 30 2019 americans reported 16 478 cases of adverse events related to tasigna according to the fda adverse events reporting system faers. Qtc prolongation causes an irregular heartbeat which may lead to sudden death. Tasigna can cause serious side effects that can even lead to death.
Tasigna can cause qtc prolongation a possibly life threatening heart problem. Increased or reduced thyroid function. Important safety information about tasigna nilotinib capsules. Tasigna nilotinib side effects range from nausea diarrhea and headaches to cardiovascular problems and irregular rhythms that may lead to sudden death.
These tests will check your heart blood cells white blood cells red blood cells and platelets electrolytes potassium magnesium cholesterol blood sugar and pancreas and liver function. Tasigna can cause serious liver effects including liver damage. Tasigna may result in hepatotoxicity as measured by elevations in bilirubin aspartate aminotransferase ast alanine aminotransferase alt and alkaline phosphatase. Drug interactions of tasigna include several drugs that reduce its break down by the liver such as amiodarone disopyramide procainamide quinidine and sotalol because the blood concentration of tasigna may be increased which may increase the occurrence of adverse effects.
The most frequently reported side effects included nausea rash headache fatigue pruritus vomiting diarrhea cough constipation arthralgia nasopharyngitis pyrexia night sweats and myelosuppression e g thrombocytopenia neutropenia and anemia. Common side effects of tasigna include. Low levels of a type of white blood cell called neutrophils. Grade 3 4 elevations of bilirubin ast and alt were reported at a higher frequency in pediatric than in adult patients.